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PharmaGen®
Helps choose the appropriate medication and its dosage
The PharmaGen® test detects variants in genes that affect the metabolism of commonly used drugs, particularly in the fields of psychiatry, neurology and internal medicine. Our genetic predisposition influences the rate of drug breakdown, its concentration in the blood, the effectiveness of treatment and the risk of side effects. Simply put, genetic analysis can help you find out what medication is right for you and at what dose, and which drugs to avoid, which can significantly speed up the appropriate treatment and increase its effectiveness.
In which situations it is appropriate to take the test
PUBLIC HEALTH INSURANCE COVERS THE TEST IN THE FOLLOWING SITUATIONS
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The prescribed medication is repeatedly failing.
- You are experiencing an increased rate of side effects.
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You have a family history of drug intolerance.
DETAILED INFORMATION
There are a number of factors that influence how drugs work in the body, but among the most important are our genes. Genetic predispositions affect the breakdown rate of a drug, its concentration in the blood, the effectiveness of treatment and the risk of side effects. If you take medicines regularly and yet your condition is not improving or you are experiencing side effects, you may be one of the more than 30% of people whose genetic makeup means they metabolise drugs differently than the general population.
Genetic predispositions can lead to altered rates of metabolism and/or different effectiveness of drugs, which means they can cause serious side effects or be completely ineffective. Knowledge of these predispositions will enable the selection of the right drug at the right dose or the right combination of drugs for a particular patient, thus significantly speeding up the deployment of appropriate treatment and increasing its effectiveness.
The PharmaGen® test detects variants in the CYP2C19 and CYP2D6 genes which metabolize more than one-third of the available drugs used primarily in the fields of psychiatry, neurology and internal medicine. These gene variants are responsible for slower or faster breakdown of drugs, leading to an increased risk of side effects or, conversely, a lack of effectiveness of the drug. The result of the genetic analysis is often decisive in choosing the appropriate treatment.
HOW DOES THE WHOLE PROCESS WORK?
After ordering the test, you will receive an email with detailed information. A DNA sample is most often obtained through an oral swab or blood sample. You can perform the oral swab yourself in the comfort of your own home using a collection kit which will be sent to you by mail together with instructions and other documents. You can have your blood drawn at your local physician's office or at our outpatient clinic. The result of the analysis will be sent to you by e-mail or by post as agreed. In the case of a positive result, we recommend an appointment for a genetic consultation.
GenScan® COMPLEX
GenScan® analysis is a modern tool for personalized prevention. It can detect the health risks hidden in your DNA, allowing you to take the necessary precautions to avoid the development of a disease or to start appropriate treatment before it occurs. With GenScan® analysis, you can get a head start on your health care, improve your quality of life and maintain your health into old age.
TromboGen®
The TromboGen® genetic analysis can detect innate predispositions to increased blood clotting and allows you to take the necessary preventive measures in time. Thrombosis is a blood clot that can cause serious health complications, in extreme cases even death. It is caused by slowed blood flow and/or altered blood composition due to the joint effects of external risk factors and hereditary predispositions.
BRCA1,2 Screen®
The BRCA1,2,Screen® genetic analysis examines the 34 most common mutations in the BRCA1 and BRCA2 genes which cause breast and ovarian cancer in women and increase the risk of prostate cancer in men. These genes are inherited independently of gender, so prevention is absolutely key across the population. This test is recommended for basic prevention, it is not a substitute for a complete BRCA1,2 gene test.
TromboGen Gravidity®
The TromboGen Gravidity® genetic analysis can detect risk predispositions for increased blood clotting, which can significantly contribute to reducing the risk of thrombosis and related pregnancy complications. Pregnant women are at risk of developing thrombosis, or a blood clot, much more than other women. This is due to the physiological changes that occur during pregnancy and possible hereditary dispositions.
Kardiogen®
The CardioGen® test can detect the risk of cardiovascular disease before the first clinical symptoms appear. Cardiovascular disease, or heart and blood vessel disease, is one of the so-called genetically determined diseases of affluence, the likelihood of which increases with age. Therefore, prevention plays a crucial role here.
Clinical exome
The most comprehensive genetic analysis that analyses approximately 4,500 genes that are associated with various inherited diseases and birth defects. It helps diagnose the cause of rare inherited diseases. Based on the results, a prognosis can be determined, a prevention or treatment strategy can be developed and the risk of recurrence of the same disease for blood relatives can be assessed.
DentalDUO (previously DentalScan®)
Periodontitis is an inflammatory disease of the supporting structure for the teeth called the periodontium. The cause is a combination of the presence of certain strains of bacteria in dental plaque and the immunological or genetic predisposition of the patient. The DentalDUO bacterial and genetic examination detects both of the above-mentioned risk factors for periodontitis, which can significantly contribute to early diagnosis, the selection of optimal treatment or the adoption of appropriate preventive measures.
Gut microbiome
The gut microbiome influences virtually the entire body, from nutrient digestion and energy absorption to immune system activity, liver function and risk of various diseases, and even the psyche. By genetically analysing a small stool sample in the laboratory, the types and amounts of bacteria that live in your colon can be determined. Together with an analysis of dietary habits, it is then possible to deduce what substances in the intestines are produced by the activity of the bacteria and how this affects the body. In addition, if we know what these bacteria need to multiply or what is not good for them, we can adjust the amount of bacteria in our gut through our diet. In this way, we can influence their impact on our body - and on our physical and mental health.
GenScan® Individual + gut microbiome + biochemical blood test (nutritional status)
Genetic testing reveals innate predispositions to disease and identifies how your body will respond to risk factors for these diseases, or what your body responds to to keep you healthy. Gut microbiome testing will show you if your gut bacteria are in balance and working with your body to maintain good immunity. In addition, the combination of these tests will tell you whether you are eliminating the risk factors hidden in your genes correctly. A biochemical blood test will reveal whether you are already developing certain risk factors and whether you are lacking certain essential nutrients.
GenScan® Individual + biochemical blood test (nutritional status)
Genetic testing reveals innate predispositions to disease and identifies how your body will respond to risk factors for these diseases, or what your body responds to to keep you healthy. A biochemical blood test will reveal whether you are already developing certain risk factors and lacking certain essential nutrients.
Gut microbiome + biochemical blood test (nutritional status)
An examination of your gut microbiome will show you whether your gut bacteria are in balance and working with your body to maintain a good immune system. A biochemical blood test will reveal whether you are already developing certain risk factors and whether you are lacking any essential nutrients.