DentalDUO (previously DentalScan®)
Reveals the risk of periodontitis
Periodontitis is an inflammatory disease of the supporting structure for the teeth called the periodontium. The cause is a combination of the presence of certain strains of bacteria in dental plaque and the immunological or genetic predisposition of the patient. The DentalDUO bacterial and genetic examination detects both of the above-mentioned risk factors for periodontitis, which can significantly contribute to early diagnosis, the selection of optimal treatment or the adoption of appropriate preventive measures.
IN WHICH SITUATIONS IT IS APPROPRIATE TO TAKE THE TEST
DETAILED INFORMATION
Periodontitis affects up to one third of the population in various forms. It is caused by untreated inflammation of the gums or the supporting structure for the teeth, which can lead to the development of chronic inflammation of the oral cavity, tooth loss, increased risk of secondary infection of the body, heart attack, stroke and in women increases the risk of miscarriage or premature birth. Periodontitis is like most other diseases, the earlier it is diagnosed and treated, the better the patient's chances of recovery.
In the beginning, the disease may be relatively unnoticeable and painless. Typical symptoms that should not be overlooked include bleeding gums when brushing, sensitive or exposed tooth necks, bad breath or wobbling teeth. The most effective prevention is thorough dental and oral hygiene and regular preventive check-ups. As a preventive measure, you can undergo a DentalDUO examination, which detects the presence of periodontitis-causing bacterial strains and the genetic make-up of the patient, including the reactivity of the patient's immune system, which can significantly contribute to reducing the risk of serious complications.
The DentalDUO test consists of two parts. The DentalBac test (can be ordered separately) detects the presence of bacterial factors involved in the development of periodontitis, which can significantly contribute to early diagnosis, the choice of optimal treatment or the adoption of appropriate preventive measures. It detects 12 basic paropathogenic bacteria:
- Highly pathogenic types:Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Filifactor alocis
- Moderately pathogenic types: Prevotella intermedia, Parvimonas micra, Fusobacterium sp., Campylobacter rectus
- Low pathogenic types: Eikenella corrodens, Capnocytophaga gingivalis, Eubacterium nodatum
The second part of DentalGEN identifies a patient's genetic predisposition to the risk of periodontitis, which can significantly contribute to early diagnosis, selection of optimal treatment or adoption of appropriate preventive measures.
HOW THE TEST WORKS AND WHAT YOU CAN EXPECT
After ordering the test, you will receive an email with detailed information. A DNA sample is obtained by swabbing the gingival sulcus. The sample is taken by a dentist using a sampling kit, which will be sent to you by post together with instructions and other documents. The result of the analysis will be communicated to you by telephone and we will agree how you wish to obtain the laboratory report. In case of a positive result, we will arrange a consultation with a geneticist who will explain everything and recommend appropriate measures.
GenScan® COMPLEX
GenScan® analysis is a modern tool for personalized prevention. It can detect the health risks hidden in your DNA, allowing you to take the necessary precautions to avoid the development of a disease or to start appropriate treatment before it occurs. With GenScan® analysis, you can get a head start on your health care, improve your quality of life and maintain your health into old age.
PharmaGen®
The PharmaGen® test detects variants in genes that affect the metabolism of commonly used drugs, particularly in the fields of psychiatry, neurology and internal medicine (blood thinners - warfarin, cholesterol-lowering drugs, painkillers - ibuprofen, antidepressants, erectile dysfunction drugs, etc.).
Our genetic predisposition influences the rate of drug breakdown, its concentration in the blood, the effectiveness of treatment and the risk of side effects. Simply put, genetic analysis can help you find out what medication is right for you and at what dose, and which drugs to avoid, which can significantly speed up the appropriate treatment and increase its effectiveness.
TromboGen®
The TromboGen® genetic analysis can detect innate predispositions to increased blood clotting and allows you to take the necessary preventive measures in time. Thrombosis is a blood clot that can cause serious health complications, in extreme cases even death. It is caused by slowed blood flow and/or altered blood composition due to the joint effects of external risk factors and hereditary predispositions.
BRCA1,2 Screen®
The BRCA1,2,Screen® genetic analysis examines the 34 most common mutations in the BRCA1 and BRCA2 genes which cause breast and ovarian cancer in women and increase the risk of prostate cancer in men. These genes are inherited independently of gender, so prevention is absolutely key across the population. This test is recommended for basic prevention, it is not a substitute for a complete BRCA1,2 gene test.
TromboGen Gravidity®
The TromboGen Gravidity® genetic analysis can detect risk predispositions for increased blood clotting, which can significantly contribute to reducing the risk of thrombosis and related pregnancy complications. Pregnant women are at risk of developing thrombosis, or a blood clot, much more than other women. This is due to the physiological changes that occur during pregnancy and possible hereditary dispositions.
Kardiogen®
The CardioGen® test can detect the risk of cardiovascular disease before the first clinical symptoms appear. Cardiovascular disease, or heart and blood vessel disease, is one of the so-called genetically determined diseases of affluence, the likelihood of which increases with age. Therefore, prevention plays a crucial role here.
Clinical exome
The most comprehensive genetic analysis that analyses approximately 4,500 genes that are associated with various inherited diseases and birth defects. It helps diagnose the cause of rare inherited diseases. Based on the results, a prognosis can be determined, a prevention or treatment strategy can be developed and the risk of recurrence of the same disease for blood relatives can be assessed.
Gut microbiome
The gut microbiome influences virtually the entire body, from nutrient digestion and energy absorption to immune system activity, liver function and risk of various diseases, and even the psyche. By genetically analysing a small stool sample in the laboratory, the types and amounts of bacteria that live in your colon can be determined. Together with an analysis of dietary habits, it is then possible to deduce what substances in the intestines are produced by the activity of the bacteria and how this affects the body. In addition, if we know what these bacteria need to multiply or what is not good for them, we can adjust the amount of bacteria in our gut through our diet. In this way, we can influence their impact on our body - and on our physical and mental health.
GenScan® Individual + gut microbiome + biochemical blood test (nutritional status)
Genetic testing reveals innate predispositions to disease and identifies how your body will respond to risk factors for these diseases, or what your body responds to to keep you healthy. Gut microbiome testing will show you if your gut bacteria are in balance and working with your body to maintain good immunity. In addition, the combination of these tests will tell you whether you are eliminating the risk factors hidden in your genes correctly. A biochemical blood test will reveal whether you are already developing certain risk factors and whether you are lacking certain essential nutrients.
GenScan® Individual + biochemical blood test (nutritional status)
Genetic testing reveals innate predispositions to disease and identifies how your body will respond to risk factors for these diseases, or what your body responds to to keep you healthy. A biochemical blood test will reveal whether you are already developing certain risk factors and lacking certain essential nutrients.
Gut microbiome + biochemical blood test (nutritional status)
An examination of your gut microbiome will show you whether your gut bacteria are in balance and working with your body to maintain a good immune system. A biochemical blood test will reveal whether you are already developing certain risk factors and whether you are lacking any essential nutrients.